Research areas | nCure Laboratory

Co-financed by the European Union

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Research areas

Our research areas span mood regulation, cognition, and receptor-driven signaling mechanisms. We study novel compounds with rapid antidepressant-like and memory-enhancing effects, relevant also for cognitive dysfunctions in neuropsychiatric disorders.

researchAreasMain

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3 169 300 PLN

Dual activity of HBK-15 – uncovering the cellular mechanisms underlying its rapid antidepressant and procognitive effects

04/2020 – 04/2026

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250 000 EUR

Collaborative learning and innovative teaching for brain drug screening

11/2023 – 11/2026

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3 015 840 PLN

Dual biased 5-HT_1A and 5-HT₇ receptor agonists activating the sigma-1 receptor in the search for an innovative selenium-based antidepressant and procognitive agent with rapid onset of action

02/2025 – 02/2029

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49 995 PLN

Evaluation of the procognitive activity of HBK-10, 5-HT_1A and D₂ antagonist with antidepressant-like properties

12/2021 – 12/2022 (Finished)

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49 500 PLN

Targeting D₂ receptor signaling pathways in mice as a chance to improve cognitive plasticity in neuropsychiatric disorders

08/2025 – 08/2026

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15 000 PLN

The role of sigma-1 receptors in glutamatergic-based cognitive impairments

01/2024 – 12/2025